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There are several matches for 'xenobiotic reductase'.
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171 matches
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organism
protein
1)
Homo sapiens
CBR1 - Carbonyl
reductase
[NADPH] 1; NADPH-dependent
reductase
with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various
xenobiotics
. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione.
[a.k.a. ENST00000530908, CH471079, SDR21C1]
2)
Homo sapiens
CYP2E1 - Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450
reductase
(NADPH--hemoprotein
reductase
). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of
xenobiotics
(Probable).
[a.k.a. R-HSA-211999, NP_000764, CYP2E1-202]
3)
Homo sapiens
AKR1B1 - Aldo-keto
reductase
family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and
xenobiotics
substrates. Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia. Reduces steroids and their derivatives and prostaglandins. Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis- retinal. Catalyzes t [...]
[a.k.a. 1T41, 2INE, ENST00000465351]
4)
Mus musculus
Akr1b7 - Aldo-keto
reductase
family 1 member B7; Reduces a broad range of aliphatic and aromatic aldehydes to the corresponding alcohols. Reduces prostaglandins. May play a role in the metabolism of
xenobiotic
aromatic aldehydes (By similarity); Belongs to the aldo/keto
reductase
family.
[a.k.a. NP_033861.2, MVDP, 1.1.1.21]
5)
Mus musculus
Cbr1 - Carbonyl
reductase
[NADPH] 1; NADPH-dependent
reductase
with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various
xenobiotics
. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2- alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S- nitrosoglutathione (By similarity) [...]
[a.k.a. NM_007620.2, Cbr, P48758]
6)
Mus musculus
Cbr2 - Carbonyl
reductase
[NADPH] 2; May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in
xenobiotic
metabolism.
[a.k.a. BC010758, P08074, F6YNX9]
7)
Mus musculus
Cyp2e1 - Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450
reductase
(NADPH--hemoprotein
reductase
). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of
xenobiotics
.
[a.k.a. ENSMUSP00000148090, NP_067257.1, CP2E1_MOUSE]
8)
Mus musculus
Akr1b3 - Aldo-keto
reductase
family 1 member B1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and
xenobiotics
substrates. Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia. Reduces steroids and their derivatives and prostaglandins. Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis- retinal. Catalyzes t [...]
[a.k.a. MGI:1353494, ENSMUSG00000001642, AC164578]
9)
Mus musculus
Akr1c6 - Estradiol 17 beta-dehydrogenase 5; Active toward androgens, estrogens, and
xenobiotic
substrates. Also exhibits low 20 alpha-HSD activity. Shows a- stereospecificity in hydrogen transfer between cofactors and substrates (A-specific). Preferentially catalyzes the reduction of 4- androstenedione, 5-alpha-androstane-3,17-dione, androsterone and dehydroepiandrosterone to testosterone, dihydrotestosterone, 5-alpha- androstane-3-alpha,17-beta-diol and 5-androstene-3-beta,17-beta-diol, respectively; Belongs to the aldo/keto
reductase
family.
[a.k.a. UPI000B3D7DAA, XP_006516573.1, AAD41250.1]
10)
Acidocella sp. MXAZ02
EKN00151.1 - COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
[a.k.a. MXAZACID_06866, K5ZLA5, NZ_JH976207.1,
Xenobiotic reductase
,
xenobiotic reductase
, ...]
11)
Acinetobacter baumannii ATCC 17978
A1S_3314 -
Xenobiotic
reductase
.
[a.k.a. ABO13703.2,
Xenobiotic reductase
,
xenobiotic reductase
]
12)
Acinetobacter baylyi
xenB - Unannotated protein.
[a.k.a. GCA_001485005_01714,
Xenobiotic reductase
, ACIAD3496]
13)
Bacillus subtilis 168
yqjM - NADPH-dependent flavin oxidoreductase; Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
[a.k.a. BSU23820, CAB14314.1, 1Z41,
Xenobiotic reductase
]
14)
Burkholderia ubonensis
XenA - NADH:flavin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. WJ32_25480, AOJ65790.1, A0A108LSI5_9BURK,
Xenobiotic reductase
]
15)
Cryptococcus gattii
CNBG_0682 -
Xenobiotic
reductase
.
[a.k.a.
Xenobiotic reductase
, A0A095C4W8, A0A095C4W8_CRYGR]
16)
Janthinobacterium sp. Marseille
xenB -
Xenobiotic
reductase
.
[a.k.a. mma_1611, ABR89505.1,
Xenobiotic reductase
,
xenobiotic reductase
]
17)
Lichtheimia corymbifera
LCOR_05641.1 -
Xenobiotic
reductase
.
[a.k.a.
Xenobiotic reductase
, A0A068RW57, A0A068RW57_9FUNG]
18)
Lichtheimia corymbifera
LCOR_05646.1 -
Xenobiotic
reductase
.
[a.k.a.
Xenobiotic reductase
, A0A068RW63, A0A068RW63_9FUNG]
19)
Lichtheimia corymbifera
LCOR_05642.1 -
Xenobiotic
reductase
.
[a.k.a.
Xenobiotic reductase
, A0A068RWJ3, A0A068RWJ3_9FUNG]
20)
Massilia timonae
xenA -
Xenobiotic
reductase
.
[a.k.a. LO55_1296, OIJ40189.1,
Xenobiotic reductase
,
xenobiotic reductase
]
171 matches
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